Protein Details: Gamma-aminobutyric acid receptor subunit gamma-3

Function

Gamma subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA); a major inhibitory neurotransmitter in the brain (By similarity). GABA-gated chloride channels; also named GABA(A) receptors (GABAAR); consist of five subunits arranged around a central pore and contain GABA active binding site(s) located at the alpha and beta subunit interface(s) (By similarity). When activated by GABA; GABAARs selectively allow the flow of chloride across the cell membrane down their electrochemical gradient (By similarity).

Sequence

PDB Structures

Ligand Binding